Cancer is a major health issue and one of the world's top causes of mortality. Innovative methods are needed to aid in the detection and treatment of different types of cancer. The use of nanobodies generated from camels as cancer therapy techniques has gained popularity recently. Nanotechnology, which uses nanobodies, is a novel and fascinating subject that holds promise for scientists hoping to progress a number of scientific domains, including medicine and oncology. Nano bodies are small biologics that have a large surface area that permits deep tissue penetration and the spread of cancer cells. They also have exceptional stability at high pH and temperature. The current research highlights the Single-domain antibodies, such as the camelid variable region of the heavy chain and the antigen-binding variable domains of the shark immunoglobulin new antigen receptor are the smallest antigen recognition domains (approximately 15 kDa) and differ from conventional antibodies in certain ways. The majority of antibodies, which are molecules that patrol our tissues and blood for invaders, are quite heavy for proteins. However, sharks, camels, and their close cousins produce smaller, simpler antibodies. Since their discovery in the late 1980s, scientists have discovered that these antibodies are extremely potent; they have the ability to attach to molecules' hidden components and pierce tissues more deeply, which increases their potential as treatments for many cancer kinds.

Keywords: pH and temperature, oncology, nanobodies, and nanoossible use of nanobodies that are naturally secreted in the body fluids of camels, Single-domain.